Any new or unusual symptom after dosing. Because this compound has little or no human safety data, there is no established list of 'expected' effects to reassure you against — treat anything abnormal as a signal.
Stop at the first clearly abnormal reaction and reassess. Keep the vial and lot number in case you need to describe what you actually took.
Any severe or fast-worsening symptom — difficulty breathing, chest pain, fainting, severe pain — is a 911 call regardless of the compound.
Allergic reaction: hives, swelling of the lips, tongue or throat, wheezing or dizziness can escalate to anaphylaxis within minutes — call 911 immediately. Site infection: spreading redness, heat, swelling, pus or fever is not wait-and-see; an abscess or cellulitis can need drainage or IV antibiotics. Unverified product: grey-market vials are frequently mislabelled or contaminated, so a reaction may be to endotoxin or the wrong contents, not the named compound.
Isolated in 1977 from the cerebral venous blood of rabbits during induced sleep, and named for that observation. No receptor has ever been identified, and no coherent mechanism has been established in nearly five decades. It crosses the blood-brain barrier, but what it does there remains unresolved.
The scientific record is thin and largely dated. Small studies from the 1980s reported inconsistent effects on sleep, and subsequent work has not clarified the picture. Modern interest is driven by marketing rather than any accumulation of evidence. Among the least substantiated entries in this library.
Not FDA-approved. No approved product anywhere.
No meaningful safety data in either direction.
No established dose. 1980s studies used small parenteral amounts inconsistently and no regimen was ever validated.
Reported from clinical trials or FDA labelling as a matter of record. It is not a recommendation, and for unapproved compounds no dose has been shown safe or effective in humans.
Above is what was administered in trials or on FDA labels, reported as fact. We do not convert it into a personal protocol, calculate a dose for your body weight, or tell you what to inject or how to reconstitute it — that decision belongs with a licensed physician. See our editorial policy.
Regulatory status changes. This page reflects our reading of public sources as of July 2026 and should be independently verified before it is relied upon.