GHRP-6 | Forge Bioenergy

Class: Growth hormone secretagogue (GHRP)
Molecular target: GHS-R1a
Sequence / structure: His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Evidence tier: Tier 4 — Preclinical Only
Category: Growth Hormone Axis

Biology & mechanism

An early hexapeptide GHS-R1a agonist. Pronounced appetite stimulation via ghrelin-receptor signalling is characteristic and often dose-limiting. Also raises cortisol and prolactin.

What the research actually shows

Extensively used as a laboratory tool for probing the GH secretagogue pathway. Some investigation in cytoprotection contexts. No approved therapeutic indication.

Regulatory status

Not FDA-approved. Prohibited in sport (WADA S2).

Safety signals

Marked hunger, cortisol and prolactin elevation. Long-term human safety not characterised.

No usage guidance is published here

Forge Bioenergy does not publish dosing, reconstitution, or administration protocols for any peptide. See our editorial policy for why. If you are considering any substance on this page, that conversation belongs with a licensed physician.

References & further reading

Primary literature search: PubMed — GHRP-6
Clinical trial records: ClinicalTrials.gov — GHRP-6
FDA compounding bulk substances: 503A bulk drug substances list
Prohibited substances in sport: WADA Prohibited List

Regulatory status changes. This page reflects our reading of public sources as of July 2026 and should be independently verified before it is relied upon.

Important notice Forge Bioenergy publishes scientific reference information only. Nothing on this site is medical advice, a therapeutic claim, or a recommendation to use any substance in humans. Many peptides described here are not approved by the FDA for any use, and several are approved only for narrow indications under prescription. We do not publish dosing, administration, or usage protocols. Consult a licensed physician before making any medical decision.