The actual hormone, made recombinantly. Binds the GH receptor directly, dimerising it and triggering JAK2/STAT5 signalling, with most anabolic effects mediated indirectly through hepatic IGF-1 production. Note the contrast with everything else in this category: somatropin replaces GH and overrides pituitary feedback entirely, whereas GHRH analogs and secretagogues ask the pituitary to make its own and leave feedback intact.
Decades of trial data across paediatric and adult GH deficiency, Turner syndrome, Prader-Willi, chronic kidney disease and other indications. The best-characterised molecule in this category by an enormous margin.
FDA-approved for multiple specific indications. Prescription-only, and notably subject to federal criminal restrictions: distribution for non-approved uses such as athletic performance or anti-ageing is a felony under 21 U.S.C. § 333(e), a restriction unique to hGH among these compounds.
Well characterised: insulin resistance and frank diabetes, oedema, arthralgia, carpal tunnel syndrome, intracranial hypertension, and slipped capital femoral epiphysis in children. Acromegalic changes with chronic excess. Contraindicated in active malignancy. Prohibited in sport (WADA S2).
Forge Bioenergy does not publish dosing, reconstitution, or administration protocols for any peptide. See our editorial policy for why. If you are considering any substance on this page, that conversation belongs with a licensed physician.
Regulatory status changes. This page reflects our reading of public sources as of July 2026 and should be independently verified before it is relied upon.